Free Radicals
Free radicals are
produced as the result of normal body processes and due to normal
environmental conditions. Most of the time, they are unable to cause
lots of damage as the body has its own defence against them, in the form
of antioxidants.
However. there are times when
these free radicals overwhelm the defence mechanisms and cause damage.
This is known as oxidative stress and has effects in the in ageing and disease
processes. Injury, stress, competition, travelling exposure to certain environmental substances
such as pollutants or allergens, can contribute to free radical
production and oxidative stress. However, it is increasingly thought
that nutrition may play an important part in helping to protect against
this damage.
Antioxidants,
otherwise known as ‘free-radical scavengers’, are the body’s natural
defence against free radical damage. Diets rich in polyunsaturated
oils increase the requirement for antioxidants, especially vitamin E.
More importantly, poor nutrition may reduce the horse’s ability to
mount a sufficient antioxidant defence. Oxidative stress may also
result following exposure to certain environmental factors such as UV
light, radiation, pollution, allergens, physical injury and exercise.
Some nutrients and
dietary components have antioxidant properties which may offer a
protective role against a number of diseases. Work has suggested that
a mixture of antioxidants may be more beneficial than a single
antioxidant in helping to support antioxidant defences
Vitamin C is water soluble
and is believed to be one of the most important antioxidants in
extra-cellular fluids. Unlike humans, primates and guinea pigs, the
horse is able to synthesise it’s own supply
Vitamin E is a collective
name for a number of biologically similar compounds which share the
same activity. A dietary source of vitamin
E is essential as unlike vitamin C, it cannot be synthesised. Vitamin
E is fat soluble and is the major antioxidant involved in maintaining
cell membrane integrity. Dietary sources of vitamin B in equine diets
include cereal grains and alfalfa.
Herbs and spices are very
valuable sources of antioxidants. At least 30 food spices and herbs
have been shown to possess antioxidant properties. For example eugenol
is the active antioxidant compound in garlic and flavenoids are found
in rosemary